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Essential Pharma and Medical Certifications... Learn = Earn

It is advisable to every one to keep updating them selves by having certifications in your relevant fields, Learning is never ending process.... n to sustain in competitive market, one must keep learning...
Here are some list of certification one can go through.
1. https://www.coursera.org/courses/…
2. https://www.udemy.com/pharmtech/
3. https://www.ptcb.org/get-certified/apply
4. www.nhanow.com/certifications/pharmacy-technician
5. www.pearsonvue.com/ptcb/
6. www.ccgp.org/exam
and there are many more certificatinos available... please keep learning to keep earning....
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Opening For Fresher's MPharm at Veeda CR

Walk in interview for Analysts 

In Bionalytical Research Department of Veeda Clinical Research



Any organization’s success depends on its team. At Veeda, we believe that every member working with us is a valuable resource of the company. Therefore we always strive to attract highly result oriented personnel, nurture and retain them with best possible opportunities.
We place a firm emphasis on openness and nurturing individual growth of our employees. We value excellence through teamwork and therefore pay special attention to various HR activities to ensure an excellent working environment and an atmosphere with equal opportunities, attractive rewards and benefits. At the time of joining we provide comprehensive induction training and mentoring to enable our employees to explore their maximum potential and perform at the highest level.
Post: Analysts
Qualification: M.Pharm./ M.Sc. B.Pharm.   
Department: Bionalytical Research
Experience: 0-6 Years
Candidates are requested to come with updated resume.
 Latest Salary proof & Educational Credentials
Candidates unable to come on said date can send their resume to hr.india@veedacr.com or courier it to HR dept, on below mention address
Veeda Clinical Research(Regd.),
Shivalik Plaza-A, Nr., I.I.M.,
Ambawadi, Ahmedabad-15.
website: www.veedacr.com


Walk in interview
Date: 28 Feb. 2016
Time: 
10:00 AM to 4:00 PM
Vanue: Vadodara - "Four Points by Sheraton" 1275,Ward No. 7. Fateh Gunj, Vadodara.
Ahmedabad - Veeda Clinical Research Vedant, Nr. YMCA Club. S.G. Highway, Ahmedabad

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Opportunity in Central Government for Pharmacist


Great Opportunity to work with Central Government
Here I am giving you all information

Job for Pharmacists (13 posts) in Central Medical Services Society -
Govt Job

Salary around Rs. 40,000/month

Central Medical Services Society, a Central Procurement Agency under Department of Health & Family Welfare, has been set up registered under Societies Registration Act, XXI of 1860 to procure and distribute health sector goods to the State Governments. The Society is looking for following warehouse staff at each of 13 locations:

Post: Pharmacist

a: RECRUITMENT RULES FOR THE POST OF PHARMACIST, CENTRAL MEDICAL SERVICES SOCIETY,

Number of Posts: 13(Locations as per Annexure-B)
Emoluments:
-In case of deputation; Rs. 9300-34,800 + Grade Pay 4200/-  
-In case of direct contract, fixed professional fee of Rs 40,000 per month
Basis of selection: Screening and interview by selection committee
Mode of Recruitment:  Either by deputation or by direct contract
Age limit: Below 45 years of age as on the date of advertisement.

Who is applicable :
Pharmacists  employed with state Governments in the same scale or in PB-1, Rs 5200-200-20200, Grade pay Rs 2800 with 5 years of service     Or  
Individuals meeting age, education and experience criterion as mentioned at Sr no7 & 8 may apply directly for recruitment on contract basis.

Educational Qualification and Experience required for recruitment:
-D.Pharma /B.Pharma degree from a reputed university / institute recognized by the Pharmacy Council of India

-An approved / registered pharmacist under the Pharmacy Act, 1948

-Minimum 8 years of post qualification experience in Pharmaceutical store /warehouse functions (preferably as store / warehouse in-charge) for D.Pharma degree holders and 6 years of post qualification experience in Pharmaceutical store / warehouse functions (preferably as store / warehouse in-charge) for B.Pharma degree holders

-Experience in Good Storage & Distribution Practices in accordance with GMP Regulations

-Exposure in handling regulatory audits on store / warehouse / distribution functions of Pharmaceutical Organisation in accordance with GMP regulations.

-Exposure to ERP and E-procurement system is desirable  g.Knowledge of local language desirable
Tenure: Tenure of deputation will be regulated as per Government of India rules.   Tenure of direct contract will be 5 years. In both cases, retention after every year of tenure will be subject to satisfactory performance as assessed by DG&CEO, CMSS

Job requirements: As per annex -1

Termination: Services can be terminated any time during tenure by serving two months notice.

Annual increase in salary: 5% subject to satisfactory performance for direct contract pharmacist and for pharmacist on deputation as per the scale.

Responsibility:
-Orderly warehousing of various categories of products like quarantine, rejected, released, returned or recalls, etc
-Implementation of Good Storage Practices
-Compliance of all statutory requirements and maintain records
-Ensure storage at recommended environmental conditions, housekeeping procedure compliances, etc
-Sampling as per the SOP
-Traceability of distributed products batch wise
-Authorized movement of man, machine and goods at warehouse  -Training of warehousing  staff on SOP
-Investigation of complaints as per the relevant procedure
-Adherence with the financial, operational and statutory compliances   -Other duties as specified by the DG & CEO or/and Reporting Officer.    

Locations:
1. Ahmedabad-Gujarat
2. Bhopal-Madhya Pradesh
3. Chandigarh-Chandigarh
4. Chennai-Tamil Naidu
5. Delhi-Delhi
6. Jaipur-Rajasthan
7. Lucknow-Uttar Pradesh
8. Mumbai-Maharashtra
9. Pathankot-Punjab
10. Patna-Bihar
11. Ranchi-Jharkhand
12. Raipur-Chhattisgarh
13. Srinagar-Uttaranchal

Last Date extended: 21st March, 2016

Get all details in advertising given in following link

Advertisement>>https://3.bp.blogspot.com/-Iz8ycjGBAWU/Vs1CTKXYgJI/AAAAAAAABl8/P6Uz95eOuBE/s1600/12744110_1131517520214101_3002106175975050714_n.jpg

Apply Online >, https://psu.shine.com/company/cmss/pharmacist_629/
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Government Jobs For Pharmacist

Urgent Recruitment of Pharmacist
Government Job for Pharmacists
Post :38 posts in State Health Society

 Salary: Rs. 15000 / month

The State Health Society is implementing Rashtriya Bal Swasthya Karyakram (RBSK) to provide health checkups for 0 to 18 years children born at public health facilities or Communities, registered with the Anganwadi Centers and enrolled in Government and Government aided schools in order to ensure their health and well being. The health checkups are to be provided by qualified doctors and team of paramedical staff by conducting field based camps in Anganwadi Centers as well as Government and Government aided schools. GoI has approved mobile team approach having AYUSH Medical Officers including ANM & Pharmacist (to assist the AYUSH doctor) to conduct health screening camps. State Health Society will be forming block level teams of two AYUSH Medical Officers, one ANM and one Pharmacist.



Walk in interview for the post of Pharmacist in State Health Society Bihar.

Post: Pharmacists
No of Posts: 38
UR- 19, EBC- 10, SC- 8, BC(F)- 1

Qualification:
Essential:
B.Pharma/D.Pharma from any Recognized University/Institution recognised by Pharmacy Council of  India.  Should be registered from Bihar State Pharmacy registration Council (BSPRC).

Desirable: Diploma course in  Computer.

Experience: At Least 1 year Experience in Health Care clinics/Institution.

Remuneration: Consolidated remuneration @ Rs. 15000/- per month

Age: Minimum Age - 21 yrs
Maximum age UR- 37, BC/EBC/Women - 40 yrs & SC/ST - 42 yrs as on 01.01.2016

Duration of Contract: The recruitment will initially be for a period of eleven months which shall be extendable annually subject to following conditions: a. Satisfactory performance,
b. Continued requirement of the position

 Roles and Responsibilities:
- Accounts / store maintenance and keep up the day to day records of De-Addiction centre.
Provide secretarial assistance to Concern officer for timely execution of activities under the Cell.
- Analyse data and compile reports.
- Any other job assigned by concerned officers.

Agreement: Selected candidate will draw a contractual agreement with DHS before joining the post.

Location: Any District of Bihar

General Information:
- Detailed Term of Reference (TOR), Qualifications / Experience / Emoluments of above positions is available in the HR Cell of the society’s official website statehealthsocietybihar.org
- Age Limit and Work Experience will be counted up to 01.01.2016.
- The recruitment will be on contract basis for a period of 11 Months, which may be extended further based on performance.
- Reservation of post will be considered as per Bihar Government.
- Non-refundable Application fee is Rs. 300/- for applicants under General category, BC/EBC Rs. 300/- and Rs. 75/- for SC/ST candidates. Application fee is to be submitted in the form of Bank Draft only. Bank Draft should be drawn on any nationalized bank favoring “State Health Society, Bihar” and payable at Patna.
- State Health Society, Bihar reserves the right to cancel any or all the positions mentioned in this

advertisement without assigning reason.

Date of Interview: 8th March, 2016 at 09:30-11:30
Vanue: State Health Society, Bihar Parivar Kalyan Bhavan, Sheikhpura, Patna - 800 014.
You can get more information on
http://164.100.130.11:8091/walkIn_info.html
Read More »

Great Opportunity In Government Jobs

Great opportunity in Government job

At

Indian Pharmacopoeia Commission

salary Rs. 25,000/- per month



The Indian Pharmacopoeia Commission (IPC) is an Autonomous Body under Ministry of Health & Family Welfare, Govt, of India primarily with the objectives of regularly updating the Indian Pharmacopoeia by publishing new edition and its addenda, National Formulary of India and other related tasks such as preparing, certification and distribution of reference substances & functions as National Coordination Centre (NCC) for Pharmacovigilance Programme of India (PvPI).

Post: Technical Associate



 No. of Posts: 40

We are looking forward for qualified personnel to fill up 40 posts of Technical Associates (for NCC & ADR Monitoring Centres) in PvPI on Contract basis having Master’s Degree in Pharmaceutical Sciences or M.B.B.S/ B.D.S/ Pharm.D or equivalent.

Preference will be given to young, dynamic personnel having experience in Pharmacovigilance and proficiency in Computer Applications.

Consolidated emolument @ Rs. 25 ,000/- per month will be paid by IPC.

The job description of the post is:-
• Collection of ADR Reports.
• Follow up with the reporter/patient for Completeness as per SOPs.
• Data Entry in VigiFlow.
• Reporting to NCC-PvPI through VigiFlow with the source data (Original) attached each  ADR case.
• Training/Sensitization/Feedback to physicians through news letter circulated by the NCC-PvPI.
• Other activities as assigned by competent authority from time to time.

 Applications are invited from citizens of India on the application format which can be downloaded from below together with the attested copies of supporting documents within 15 days from the date of advertisement.

The competent authority reserves the right to increase or decrease the number of vacancies and rejection and/or all applications received w ithout assigning any reason. Selected candidates shall be posted in any of the AMCs under PvPI across the country/NCC - PvPI, IPC, Ghaziabad

INDIAN PHARMACOPOEIA COMMISSION
MIN.OF HEALTH & FAMILY WELFARE
GOVERNMENT OF INDIA
SEC-23, RAJ NAGAR
GHAZIABAD–201 002

Last date: 2nd March, 2016

Get all notification on
http://ipc.nic.in/showfile.asp?EncHid=&lid=500

Download format

http://ipc.nic.in/showfile.asp?lid=343&EncHid=
Read More »

Vacancy in Food & Drug Administration

Opportunity to work as DRUG INSPECTOR (5 posts) under Food & Drug Administration

MPSC invites applications by online method for post of Drug Inspector under Food & Drug Administration, Medical Education and Research Services. For these vacant positions, candidates can apply by following below rules.

Post: Drug Inspectors
No of posts: 05

Pay Scale: Rs. 9300-34800

grade pay 4400/- plus other allowances

Candidate should be Indian national.

Age: not more than 45 years (As on 1 July, 2016)

Qualification:
Possess a degree in Pharmacy or Pharmaceutical Chemistry or Medicine with specialization in clinical Pharmacology or Microbiology from a University established in India by law.


EXPERIENCE:
Possess practical experience gained after acquiring above qualification in the manufacture or testing of drugs or enforcement of the provisions of the Act for a period of not less than three years.

Preference may be given to the candidates having a post graduate degree in the subject mentioned in para 4.5 or research experience in the synthesis and testing of drugs

Exam Fee: UR-Rs 523;

Backward caste- Rs. 323

Any candidate will fill up incorrect information, not be eligible for recruitment.

Last date to apply online : 8th March, 2016

APPLY ONLINE >

https://mahampsc.mahaonline.gov.in/MPSC/MPSCHome.aspx
Read More »

Carrier in Junior Pharmacist

Career as Junior Pharmacist in GCRI

The Gujarat Cancer & Research Institute (GCRI), established in the year 1972, is a functional autonomous body jointly managed by Government of Gujarat and Gujarat Cancer Society. It is also a Regional Cancer Centre of Government of India and getting assistance under National Cancer Control Programme. GCRI is a unique example of cooperation between State Government, Central Government and Non-Government Organization.

Post: Junior Pharmacist
No.of post: 03- Gen

QUALIFICATION: Degree of Pharmacy or a Diploma in Pharmacy from a recognized University or an equivalent education qualification and must have registered his/her name with the Pharmacy Council.

AGE: Not more than 30-years can be relaxed for deserving case.

EXPERIENCE: Two years experience of Pharmacy work in any Hospital or Institute will be Preferred. (If experienced candidates are not available fresher may be consider as Trainee).

PAY: Rs.8,000/- P.M (Consolidated).

Interested candidates may apply upto 29-02-2016,Monday during office hours, in the application form downloaded from our website. Photocopies of all educational qualifications, experience certificates & attempt certificates duly self attested along with one recent color passport size photograph to be submitted by the post / courier / in person to The In charge Director, The Gujarat Cancer & Research Institute, Civil Hospital Campus, Asarwa, Ahmedabad – 380016.

Note: Candidates applying through E-mail must send hard-copies of all other documents related to educational and experience certificate etc. before last date of submission of application. Application received without document will be outrightly rejected.

Candidates are requested to send all self attested photo copies of following documents with application form.
- Detailed Bio-data
- Birth Certificate
- Caste Certificate
- All Mark Sheets of Graduation, Post Graduation, Super Speciality , etc.
- MCI Registration of Graduation, Post Graduation
- Gujarat State Medical Council Registration / or other State’s Medical Council Registration
- Attempt Certificate of Graduation, Post Graduation
- All Experience Certificates
- NOC from Present Employer

THE GUJARAT CANCER & RESEARCH INSTITUTE
NEW CIVIL HOSPITAL CAMPUS, ASARWA, AHMEDABAD-380 016
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Opportunity For Pharmacy Graduate in Central Government

It's a Great opportunity for Pharmacist

 In a Central Government 

Grab this opportunity

It will start from 23rd February 

You can get all details through this link


See more Details in Advertisement

Government vacancies for Pharmacists
 (54 Posts) in CRPF | All India level

Applications are invited from male/female Indian citizens to fill up the following posts of Group “B” and “C” non ministerial, non gazetted, combatised paramedical staff in CRPF on all India basis. The posts are temporary but likely to become permanent.



Post: Assistant Sub-Inspector (Pharmacists)

No.of post: 54
General/UR- 25, UR-Ex-Servicemen- 03, OBC- 12, OBC Ex-Servicemen- 02, SC- 07, SC Ex-Servicemen- 01, ST- 04

Scale of pay: PB-2 Rs.5200 - 20200 plus Grade Pay Rs.2800/- per month

Education qualification:
a) Intermediate or 10+2 or equivalent from a recognized Board or University; and
b) two years Diploma or Degree in Pharmacy granted by an institution of the Central Govt. or State Govt or an Institution recognised by the Central Govt. and State Govt ; and
c) should be registered as a Pharmacist under the Pharmacy Act 1948 (8 of 1948)

Age: Between  20 to 25  years as  on 01.08.2015

Note:
Candidates who have not acquired the educational qualification will not be eligible and need not apply.
i) Candidates selected for appointment are liable to serve any where in Indian Territory and abroad.
ii) The numbers of vacancies given above are tentative and may increase or decrease at any time/stage of recruitment process, due to administrative reasons.
iii) The posts are combatised and purely temporary in nature but likely to continue.
iv) New contributory pension scheme to Central Govt. Employees which has come into effect from 01.01.2004 will be applicable to all selected candidates.
v) If vacancies of ex - servicemen remain unfilled due to non - availability of eligible or qualified candidates, the same shall be filled up by candidates from non ex - servicemen candidates of respective category.

RELAXATION:
The children and dependent family members of those who were killed in the riots of 1984 and Gujrat riots of 2002 would be eligible for relaxation in age by 5 years. If the applicant belongs to SC, ST and OBC category, the relaxation so provided in the clause will be in addition to the age relaxation as applicable in above. To obtain this relaxation a certificate from the concerned District Magistrate/District Collector of the district where the victim was killed, should be attached with the application.
[23/02 3:50 pm] Sohel Punasiya: RECRUITMENT CENTRES
The recruitment tests will be conducted at following 08 recruitment Centres. The candidates can prefer any one of the recruitment Centres for recruitment tests. Recruitment tests of a particular candidate will be conducted at same recruitment Centre where he/she will preferred for the centre.

1 Composite Hospital, CRPF, New Delhi
2 Composite Hospital, CRPF, Hyderabad
3 Composite Hospital, CRPF, Guwahati
4 Composite Hospital, CRPF, Jammu
5 Composite Hospital, CRPF, Allahabad
6 Composite Hospital, CRPF, Ajmer
7 Composite Hospital, CRPF, Nagpur
8 Composite Hospital, CRPF, Muzaffarpur

EXAMINATION FEE
Male candidates belonging to General (UR)/ OBC category applying for recruitment to the above posts should deposit Rs.100/- (Rupees one hundred)only for Group - ‘ B ’ & Rs.50/- (Rupees fifty) only for Group- ‘C’ as examination fee through following mode :
(1) Through SBI Challan(Challan other than SBI will not be accepted).
(2) Net Banking through any bank.
(3) Credit card /Debit card of any bank .
(4) E-payment through E-Challan of post office only (No other mode through Post Office will be accepted). Details of remittance particulars are also mentioned in the online application.

MODE OF PAYMENT:
(i) The payment of Examination fee will be On-line mode.
(ii) For payment of Examination fee, candidate should click on payment mode column in part-III of application form and he will be connected to payment website as per following procedure.
(iii) The facility and complete process/guidelines for submitting online applic ation is available on website i.e. www.crpfindia.com and www.crpf.nic.in(Through link as Recruitment> View all > Paramedical Staff ‘Apply ’).
(iv) Women candidates and candidates belonging to Scheduled Caste, Scheduled Tribe and Ex- Servicemen eligible for reservation are exempted from paying fee.

HOW TO APPLY
The candidates can choose only one post at the time of submitting their on line application otherwise candidature will be cancelled. Since written examination for all the posts will be conducted on same date/time on all India basis and also there will be different question papers for different posts, it is advisable that candidates should apply for only one post as it will not be possible for them to appear for written test for more than one post on same date/time.
[23/02 3:50 pm] Sohel Punasiya: GENERAL INSTRUCTIONS AND CONDITIONS:
1. The Examination will comprises of Physical Standard Test, Physical Endurance Test, Written Examination, Screening of documents, Trade Test & Medical Examination.
2. A candidate in whose case a certificate of eligibility is necessary will be admitted to the Examination provisionally. Candidates are advised to go through the requirements of educational qualification, age, physical standards, etc. and satisfy themselves that they are eligible for the posts, before applying. When scrutiny is undertaken at any stage(at PST and finally at Skill/Trade Test), if any claim made in the application is not found 28 substantiated the candidature will be cancelled and the department decision in this regard shall be final.
3. BEFORE APPLYING, CANDIDATES IN THEIR OWN INTEREST ARE ADVISED TO GO THROUGH THE DETAILED INSTRUCTIONS CONTAINED IN THIS NOTICE CAREFULLY. THIS NOTICE IS ALSO AVAILABLE ON THE WEBSITE OF THE CRPF (www.crpfindia.com and www.crpf.nic.in (Through link as Recruitment > View all > Paramedica Staff ‘ Apply’).
4. Candidates seekingres ervation benefits for SC/ST/OBC/EXM must ensure that they are entitled to such reservation as per eligibility prescribed in the Notice. They should also be in possession of the certificates in the format prescribed by Government of India in support of their claim.
5. Candidates belonging to the Physically Handicapped category are not eligible to apply for this examination.
6. Central Government civilian employees claiming age relaxation should produce a certificate in the prescribed format from their office at the time of document verification in respect of the length of continuous service which should be for not less than three years in the immediate period preceding the closing date for receipt of application. They should remain Central Government civilian employees till the time of appointment in the event of their selection.
7. Only a single application will be entertained. IN CASE OF MULTIPLE ONLINE APPLICATIONS, THE LAST APPLICATION FOR WHICH PART-I, II AND PART-III REGISTRATION HAVE BEEN COMPLETED WILL BE ACCEPTED.
8. MOBILES AND OTHER ELECTRONIC GADGETS ARE BANNED WITHIN THE PREMISES OF THE EXAMINATION CENTRE. POSSESSION OF SUCH EQUIPMENT WHETHER IN USE OR IN SWITCH OFF MODE, DURING THE EXAMINATION WILL BE CONSIDE RED AS USE OF UNFAIR MEANS. CANDIDATURE OF SUCH CANDIDATES WILL BE CANCELLED. THEY WILL BE LIABLE FOR FURTHER ACTION INCLUDING INITIATION OF CRIMINAL PROCEEDINGS AND DEBARMENT FROM CRPF EXAMINATION UPTO 5 (FIVE) YEARS, AS MAY BE DECIDED BY THE DEPARTMENT.
9. CANDIDATES SUBMITTING ON LINE APPLICATIONS SHOULD RETAIN THEIR REGISTRATION NUMBER ASSIGNED TO THEM ON LINE FOR CORRESPONDENCE WITH THE CRPF. THEY SHOULD NOT SUBMIT PRINT OUTS OF THEIR APPLICATION TO THE DEPARTMENT. THE FACILITY OF ON -LINE APPLICATION WILL BE AVAILABLE AT WEBSITE www.crpfindia.com and www.crpf.nic.inThrough link as Recruitment View all > Paramedical Staff ‘Apply’) UPTO 23 .03.2016. HOWEVER, CANDIDATES ARE ADVISED TO KEEP A PRINT OUT COPY OF APPLICATION WITH THEM.
10. Candidates may contact on help line No.011-24368630 for any query , in respect of filling/submitting applications.
11. Candidates must carry at least one photo bearing IDENTITY PROOF in original such as Driving Licence, Voter Card, Aadhaar Card, Pan Card etc. to the examination centre, failing which THEY SHALL NOT BE ALLOWED TO APPEAR FOR THE EXAMINATION.
12. In case the scanned photograph(s) appearing in the CRPF copy of Admit Card and or on Attendance Sheet is not clear invigilators are required to verify the identity of the Candidate with reference to the photo ID Proof and get colour photographs pasted on the Department copy of Admit Card and or on Attendance Sheet. Accordingly, candidates should bring passport size colour photographs for affixing in the Department copy of Admit Card in the presence of Invigilator. Candidates not carrying photographs will not be allowed to appear in the examination.
13. Candidate submitting more than one application with different particulars like name, fathers name, community/Photo(Face)/Educational and/or Technical Qualification will be summarily rejected and also be deba rred from the examination. A candidate will also be debarred from examination of department for a specified period/or life time if
(i) the candidate submits application for a particular post to more than one 29 centre, (ii) the candidate submits multiple appl ications for the same post and category, (iii) The candidate submits multiple applications with different community for the same post and category, (iv) The candidate submits multiple application with different photo(Face) and different name for the post a nd category and (v) The candidate submits multiple application with different documents for same post and category.
14. Signatures of the candidates on all prescribed documents should be identical, either in English or Hindi, and must be in running hand and not in block/capital or disjointed letters. Signatures in different style or language at the time of different process and document verification etc. may result in cancellation of candidature.
15. Candidate should note that only Name, Father’s name and Date of Birth as recorded in the Matriculation/High Schoo/Examination Certificate or an equivalent certificate as on the date of submission of application will be accepted.
Note: In case candidate has changed his/her name than gazette notification or any other legal documents as applicable should be submitted at the time of document verification. Such candidate should indicate their changed name in the online application. However, other details should match with the Matriculation or equivalent certificate. Date of such change should be prior to submission of application.
16. No documents including online application form is required to be sent, however, all the applicants are advised to keep a copy of online application form with them along with proof of payment (a Copy of challan/online payment receipt) for their record & to be produced at the time of PST/PET and whenever required.
17. Candidates are advised to upload their “Admit Card/Call Letters” stage wise from CRPF websitewww.crpfindia.com and www.crpf.nic.in Through link as Recruitment > View all >Paramedical Staff ‘ Apply ’ ) only if he/she qualified in previous stage well before commencement of next phase/stage of recruitment. He/She should browse the website regularly.

Opening date for registration: 23-02-2016
Closing date for egistration : 23-03-2016

Advertise Number: R.II-01/2015 

 



Read More »

More Job Opportunities For Phamacy Fresher's

Here is one  more Opportunity for Freshers & Experienced PG.

 Veeda Clinical Research  Pvt. Ltd.


Experience required for the Job: 0 - 6 years

Annual Salary of the Job: 0.0 - 6.0 Lacs

Job Location: Ahmedabad

Apply Now

Dear Candidate,

Greetings from Veeda Clinical Research Pvt. Ltd.

We have suitable opening which matches to your current role as described in your resume.please find the details of position as under:

Job Title:Analyst

Department:Bioanalytical Research

Qualifications:M.Pharma (Quality Assurance/ Pharma. Chemistry)
M.Sc. (Analytical Chemistry/ Biotechnology)/ B.Pharma

Experience:0 to 6 Years

Special Skills:Good Communication

Job Responsibilities:
  • Bio analytical method development.
  • method validation and project sample analysis
  • Sample Preparation in bio analytical lab as per method SOPs
  • Biological Sample Movement (e.g. to manage biological plasma sample, blood sample, urine sample, serum samples etc.) Operation 
Maintenance and calibration of equipments (refrigerated centrifuge, pH meter, analytical balance, micropipettes, HPLC, LCMS etc.)
  • Maintaining the equipment log(s)
  • Review bioanalytical data
  • Inform group leader about the progress or completion of the assigned activity
  • Standard Operating Procedure (SOP) preparation
  • Contingency arrangement
  • Maintenance of displays (labels, SOPs, Charts etc.)
  • Supervision of the general laboratory activities
  • Reply to relevant QC/QA queries in co-ordination with team members
  • Execution and maintenance of GLP, GCP, Safety and Quality systems


Interested Candidates Send their Resume on Given Below ID:
ravindra.jadav@veedacr.com

Thanks & regards
Ravindra Jadav
Human Resource
Veeda Clinical Research
Ahmedabad,India
Cell : 9909904301
Read More »

Vacancy in Two Companies

Dear All

Here is Two Companies recruitment

1) In Apotex Banglore require

B.pharm fresher 10 male candidates
for production Dept.

Please forward CV , on
abannatt@apotex.co.in

2) Vacancy for microbiologest

at Solrex pharma Baddi ...
Interested candidate may send his CV to anil.makwana@sunpharma.com
Read More »

Jobs Vacancy For Freshers

Job Vacancy at Ahmadabad,

 fresher and experience for Mpharm

Name : Saviour Pharmaceuticals.

Qualification : Mpharm Regulatory Affairs

Salary : 12000 per month + Bonus

Interested candidates email your CV to exports@saviourpharma.com.

Please note mandatory to mention : Reference by Ms. Pooj Parmar.
Read More »

Opening For Fresher's

Opportunity For Fresher's  & exp.

 Pharmacists in Apollo Hospitals -

There are  50+ posts


Apollo pharmacy is a leading retail chain of pharmacy and is a unit of - Apollo Hospitals Enterprise Ltd. - Asia's largest healthcare group.
Our growing Retail Pharmacy network touches lives across the length and breadth of India and we serve 200000+ customers a day. With over 30 years of retailing experience, customer-focused service and brand value our network spans out to 2000+ retail pharmacies through which we have been serving our customers for their healthcare needs 24x7.*
Post: Pharmacist / Supervisor
No.of post: 50+
Job Description:
* Dispensing the drugs as per prescription / Indents.
* Raising the Pharmacy Requisition slips as per requirements.
* Receive the stock from Stores and check against the Issue Slips, for quantity, batch no, expiry etc.
* Doing physical verification of stocks with computer data daily.
* Taking the stock of short-expiry medicines once a month.
* Taking the stock of non-moving medicines once in 6 months.
* Building customer relationship for effective service towards total patient care.
Candidate Profile
Qualification: D.Pharm & B.Pharm
Experience: 0-8 Years
MUST BE REGISTERED IN GUJARAT PHARMACY COUNCIL.
Additional Information:
Experience:
 0-8 years
Qualification:
 D.Pharm, B.Pharm
Location: 
Gujarat- Ahmedabad / Anand / Baroda / Surat
Functional Area: 
Pharmacist
Industry Type: 
Apollo Pharmacist
Employment Type: Full Time

Salary: 
No Bar for Right Candidate
End Date:
 15th March, 2016
Walk - In Interview
Tuesday to Friday
Timing: 10:30 AM to 1 PM
Venue: 19,Sayona Silver Estate, Opp, B.P.C. Mixer Plant, Near Silver Oak Club,Gota Ahmedabad.-380 054.
Walk - In Interview or Contact on (079) 7600041602
Posted by,
Kapil Bhatt,
Apollo Hospitals Enterprise Ltd.
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Open Position at Piramal Enterprises Limited

Discover the Scientists and Expert In You

Piramal Enterprises Ltd ,Pharmaceutical Development services, Ahmedabad is a world class leader in contract research for Formulation Development  for NCE ,NDDS, and generic serving the top pharma companies of the world .

Formulation  Development 
Sr. Research Associate-FormulationDevelopment 
Qualifications : M.Pharm Pharmaceutics , pharmaceutical technology 
Experience : 2-4 years 
About Role : Good exposure in formulation development  (OSD) preparation  & execution development of technical document.  Execution of scale up &pilot batches under GMP conditions

Sr. Research Scientist 
Qualifications : as above or PhD 
Experience :6-8 Years 
About Role:Delivery of formulation project within time limit ,cost & specifications . Manufacture of batches byou USFDA, GMP norms ensuring good notebook documentation GDP. 

Analytical Development 
Senior Research Associate- Analytical Development 

Qualifications : M.Pharm Pharmaceutical chemistry , MSc Analytical chemistry 
Experience :2-4 Years
About Role: Method development ,Routine analysis of formulation sample,calibration of analytical instruments and method verification /validation of different analytical methods.

Sr. Research Scientist 
Qualifications : as above or PhD
Experience :6-8 Years
About Role : preparation of analytical method development & validation report, SOP Preparation  and training to new joiners, preparation of technical document about products specificaction ,COA, STP, validation of protocol, planning of  day to day work and coordination of team. ,ensure cGLP practices in Labs.

Venue :
Piramal Enterprises Ltd 
Pharmaceutical Development Services (Ahmedabad)
Plot no-19 Pharmaceutical economical Zone, 
Village -Matoda Sarkhej Ballater NH#8A
Taluka-Sanand-Ahmedabad, Gujarat. 382213

Date: 13th February 

Time: 10.00 am to 4.00 pm

Phone: +912717669100

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Opportunity In Regularity Affairs

Kinapse India Scientific, Service 


Opportunity -Regularity Affairs

Here is the chance for you to work in Regularity Affairs  with one of the fastest growing life science organisation.

An opportunity to be part of winning team with a global exposure to Regularity Affairs.

Hiring 

  • Regularity Affairs Generalist 
  • Regularity Affairs Publisher 
  • Regularity Affairs CMC Specialists
Walk In : Saturday 20th February  & 21st February Sunday  21 February 2016.

Time: 9:00 am to 5:00 pm

Venue : Kinapse India Scientific Service,  Banglore 
Second floor, block  N-1 ,Manyata embassy business Park, outer ring road, Nagawara,Banglore -560045 

Advance application sent at recruitment@kinapse. Com shall be allocated interview slots for 20th February, other welcome to walk in  21th February. 

Desired Profile :
  • Education&Experience : For Regularity, M.Pharm with 2 years & B. Pharm-M.Sc. with 6 years relevant experience. 
  • Significant knowledge on Regularity requirements and guide line, post approval on CMC documentation ,authoring and reviewing  module 1&-3 with exposure to various document  management publishing software preferred. 
  • Excellent verbal and written communication skills. 
For more details about the profile please visit :

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Urgent Vacancy in MNC Pharmaceutical And Certified course


  • Urgent Vacancy at Amneal Pharmaceuticals


In Formulation & development

solid oral, 2-4 years, US market

Interested candidate can send their resume on tarunp@amnealindia.com


  • Certificate Course at KBIPER Dates of Conduct and course title


19 - 20 Feb 2016 - QbD Principles: Applications in Pharmaceutics

25 – 26 Feb 2016 - Good Clinical Practices

4 – 5 March 2016 - Basic operations and troubleshooting in HPLC and spectrophotometer

12th March 2016 - Regulatory guidelines of different countries for product approval

18 – 19 March 2016 - Hands on training on basic cell culture techniques

Registration Form Link:
http://goo.gl/forms/IpAIb1pt73
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Opening In MNC pharma

Walk-In For QA-QC 

At Ahmedabad for Liva Pharma, Injectable, Vadodara

Company: Liva Pharmaceutical, Zydus Cadila Group
Experience: 2 to 7 yrs

Salary: INR 3,00,000 - 6,00,000 P.A

Location: Vadodara/Baroda

 Job Description
 
Walk-in @ Ahmedabad 07th February 2016.

LIVA Pharmaceuticals Ltd.(Zydus Cadila)

Liva Pharmaceuticals Limited - a Zydus Group of company is setting up a state-of-art injectable products manufacturing facility at Vadodara (Village : Jarod, Vadodara-Halol Highway).

The plant will manufacture Liquid Vials, Lyophilised products, Pre-filled syringes and cartridge products.

Inviting young and enthusiastic professionals for the following vacancies:

Sr. Associate - Quality Assurance - B. Pharm/M. Pharm, having exposure of IPQA activities, deviations, Change Control, CAPA handling, in-process Sampling, risk analysis

Sr. Associate - Validation - B. Pharm/M. Pharm / M. Sc., having exposure in qualification of water systems, HVAC, Autoclaves, vessels, Washing Machines, Depyrogenation tunnel, filling machine, lyophilizer, and media fill, equipment risk analysis

Sr. Associate - Quality Control - B. Pharm/M. Pharm/B. Sc./M. Sc, having exposure of analysis of water sample, RM, PM, Finished product samples, handling of HPLC, GC, IR, UV.

Sr. Associate - Microbiology (QC) - B. Sc./M. Sc. (Microbiology), having exposure of handling of media preparation activity, BET, Sterility test, Microbial Culture identification and handling , Media Fill, Environmental Monitoring, Water testing

For all the above positions candidates should have 2 to 10 years of experience in highly regulatory market, in injectable formulation facility.

Interested candidate may Walk-In for Interview along with their CVs and relevant documents as per the schedule below;


Date : 07th February (Sunday)

Time : 10:00 a.m. to 04:00 p.m.

Venue : Gurudwara Govinddham Lane,
               Near Mondeal Business Park,
               Thaltej, S.G. Highway,
               Ahmedabad, Gujarat 380054

Those unable to attend the Personal Interview, may send their resume through e-mail to hr.liva@zydusmail.com.
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The Miraculous Tree

Kadamba : A magical tree having enormous pharmacological action

   
The Cadamba is one of the important medicinal plants belonging to the Rubiaceae family. It is crucially significant as it has the largest number of phytochemicals and secondary metabolites (viz., cadambagenic acid, cadamine, quinovic acid, β-sitosterol, cadambine, etc.) having pharmacological and biological properties. It can be used as an alternative to various synthetic chemical compounds in the prevention as well as the treatment of several incurable diseases. More than 100 years of research has been done to discover various phytochemicals and their implications. Very few of them, i.e. ≤2% have been commercialized due to the lack of a suitable model system as well as various associated controversial issues. The solubility of phytochemicals is another major concern: Further response that will be generated due to the solvent used is also unpredictable. Moreover, the Cadamba is one of the ornamental plants with religious significance. Here we have made an effort to summarize all the phytochemicals and their significance to render the interest that would help in their commercialization.
Keywords: Anticancer, antioxidant, Cadamba, pharmacology, phytochemical


    Introduction  


There is a number of flora in use for medicinal purposes over the past several centuries. Countries such as China, India, and Egypt are well known for the active usage of medicinal plants in the treatment of various incurable diseases. India is the largest producer of medicinal herbs in the world due to which it is often called a botanical paradise. Ayurvedic science is deeply rooted in India and its neighboring countries. It was developed even before the medieval period, when people had little knowledge of science. There is a number of ancient therapeutic measures based on medicinal plants that have been developed in India. [1],[2],[3] They can cure several diseases and ailments such as diabetes, cardiovascular disorders, cancer, and liver damage. [4],[5],[6] A variety of plants is used for medicinal treatments; either whole or in specific part/s (bark, root, leaves, fruit, flowers, seeds), in the dried state. These are consumed using water, sugar, salt, honey, etc. Now they are formulated into suitable preparations such as tablets, pills, extracts, tinctures, lotions, ointments, and creams. [6],[7]

The Cadamba is commonly known as "Kadamba" in Sanskrit and Hindi and as "Kodom" in Bengali. It is an evergreen tropical tree found in different parts of India, Bangladesh, Nepal, Myanmar, Sri Lanka, Cambodia, Laos, Philippines, Malaysia, Indonesia, Papua New Guinea, and Australia. The other names of the plant are Neolamarckia cadamba, Nauclea cadamba (Roxb.), Anthocephalus cadamba (Roxb.) Miq.,Samama cadamba (Roxb.) Kuntze, Anthocephalus morindifolius Korth., Nauclea megaphylla S. Moore, Neonauclea megaphylla (S. Moore) S. Moore, etc. The species has been widely but incorrectly called Anthocephalus chinensisas it has scented orange flowers present in dense globe-shaped clusters, which are used in the preparation of perfumes. It is an ornamental plant that is also used for timber- and paper-making. It has crucial significance in Indian mythology and religion. Various religions in India have strongly believed that God lives inside a Cadamba tree based on its enormous significance to humankind. It has been said in the Sanskrit shloka,"Ayi Jagadamba Mad-Amba Kadamba Vana-Priyavaasini Haasa-Rate," that is, Goddess Durga likes to live in the forest of Cadamba trees.

The Cadamba is a large tree with height of ~ 45 m with a broad umbrella-shaped crown and straight cylindrical bole. It grows very quickly in length but takes 6-8 years to increase its girth. Its trunk has a diameter of 100-160 cm, while the leaves are 13-32 cm long. Flowering usually begins when the tree is 4-5 years old. The fruits of the Cadamba are small, containing fleshy capsules packed closely together to form a yellow-orange infructescence. The Cadamba has been known to cure a number of diseases; particularly, the extract prepared from the bark and leaves is crucial. [8] Various researchers across the world have focused their studies on discovering a number of phytochemicals as well as secondary metabolites (saponins, indole and quinoline alkaloids, secoiridoids, and triterpenes) with pharmacological significance from theCadamba. The present review is based on the significance of the Cadamba and its derived products to humankind.

Localization 

In India, it is found in the temperate Himalayas (which extend from Kashmir to Bhutan), Garhwal, Himachal Pradesh, Sikkim, Assam, and Manipur. In Garhwal, it is particularly distributed in the temperate zones of Pauri, Tehri, Chamoli, and Uttarkashi districts, while in Himachal Pradesh it is prevalent in the districts of Chamba, Kangra, Manipur, Bilaspur, Kullu, Sirmour, and Simla at the elevation of ~ 2 km. Besides India, theCadamba is found in Nepal, Myanmar, and western China. [13],[14],[15] 

Composition

• Heartwood

Dihydrotectochrysin, dihydrowogonin, pinocembrin, chrysin, naringenin, kaempferol, aromadendrin, quercetin, taxifolin, 7-hydroxy-5, 2΄, 4΄-trimethoxyflavanone, 2΄-hydroxy 2, 4, 4΄, 6΄- tetramethoxychalcone, 2΄, 4΄ dihydroxy-2, 4, 6΄- trimethoxychalcone


  I. Phytochemicals from stem bark of Cadamba; (a) Padmakastein (b) Tectochrysin (c) Leucocyanidin (d) Chrysophenol (e) Emodin (f) Physcion (g) Sakuranetin (h) Puddumin B (i) Taxifolin. II. Phytochemicals from the stem of Cadamba; (a) Apigenin (b) Sakuranetin (c) Prunetin (d) β-sitosterol (e) Kaempteritrin (f) Ursolic acid (g) Afzelin (h) n-octacosanol (i) Triacontane (j) n-octacosanol (k) Oleic acid. III. Phytochemicals from heartwood of Cadamba; (a) Chrysin (b) Naringenin (c) Dihydrowogonin (d) Dihydromethycitin (e) 2´-hydroxy 2, 4, 4´, 6'-tetramethoxychalcone (f) Kaempferol (g) Quercetin. IV. Phytochemicals from leaves, branches, and root bark of Cadamba; (a) Quercetin-3-rhamnoglucoside (b) Amygdalin (c) Ursolic acid (d) Stigmasterol (e) Prunetinoside. V. Commercially significant phytochemicals from Cadamba; (a) Cadambagenic acid (b) Cadamine (c) Quinovic (d) β-sitosterol (e) Cadambine (structures are drawn using Chemdraw)

Click here to view



• Stem

Narigenin, apigenin, β-sitosterol, sakuranetin, prunetin, genkwanin

• Sapwood

7-O-(β-D-glucopyranosyl)-5-O-methylnaringenin, genistein, prunetin, n-pentacosane, triacontane, noctacosanol, 0β-sitosterol, ursolic acid, oleic, palmitic, stearic acids, afzelin, kaempteritrin, naringenin, β-sitosterol glucosid.

• Stem bark

Padmakastein and its derivatives, β-sitosterol behenate, tectochrysin, genistein, leucocyanidin, 4΄-glucoside of genkwanin, chrysophenol, emodin, 8 β-D glucosides, orientalone, physcion, β-sitosterol glucoside, amygdalin, prunasetin, sakuranetin, puddumetin, flavanone, sakuranetin (5, 4΄-dihydroxy-7-methoxy flavone) and its 5-glucoside, neosakuranin (2, 4΄-dihydroxy-4-methoxy-6-glucosidoxychalcone), leucocyanidin, puddumin B, naringenin-4΄-methylether-7-O-β-D-galactoside), taxifolin .

• Root bark

Ursolic acid, stigmasterol, prunetinoside, glucogenkwanin

• Seed

Naringenin-5-O-α-L-rhamnopyranoside, 4΄-O-methylliquiritigenin-7-O-α-L-rhamnopyranoside, naringenin 4΄-methylether 7-xyloside, β-sitosterol-3-O-D-galactopyranoside


• Branches

Substitute of hydrocyanic acid, amygdalin [Figure 1]

• Leaves

Quercetin-3-rhamnoglucoside, kaempferol 

• Commercially available

Cadambagenic acid, quinovic acid, β-sitosterol, cadambine, cadamine 

Significance

Astroethnobotanical importance

According to mythology, the whole universe is made of five elements or panchtatva (fire, earth, air, soil, and water), including plants and animals. The vast Sanskrit literature has affirmed that not only human beings but even minute creatures, whether plants, animals, or microorganisms, are under the influence of the forces of the planets. It is believed that each and every person born on Earth belongs to any one of the 27 nakshatras (stars) present in the universe. There are 27 stars, which are correspondingly correlated to 27 trees present on Earth as given in [Table 1]. This correlation signifies that humans are directly related to plants. These 27 celestial plants have the power to fight against the harmful effects of the planets on human lives. Plants and herbs have been found to be extremely effective in neutralizing the detrimental influences of the astral positions of stars. The Cadamba is one of the trees enlisted in [Table 1], which resembles Satabhisha nakshatra. It has been indicated in astrology that humans having Satabhisha as their birth star should plant the Cadambanear their habitats, which would help in curbing mental depression, heart attack, mood swings, 



Antivenom activity

Snakebite is one of the major causes of the high mortality rate in India and other developing countries. Various antivenom immunotherapies have been developed for specific treatment against snake venom envenomation. There are various side effects of such therapies, viz., anaphylactic shock, pyrogen reaction, and serum sickness. Most of these symptoms may be due to the action of higher concentrations of non-immunoglobulin proteins present in commercially available hyperimmune antivenom.

Over the years, many attempts have been made for the development of snake venom antagonists, especially those with plant origin. Many ethnobotanical survey reports and books were published highlighting the use of plant drugs for the management of snakebites. Many Indian medicinal plants are recommended for the treatment of snakebite. It has been found that methanolic extract of the root bark of theCadamba can be used as an antidote against snakebite. It is used in neutralizing Vipera russellii and Naja kaouthia venom, which can induce hemorrhage, cardiotoxicity, neurotoxicity, defibrinogenation, and inflammation. The pentacyclic triterpenes (free or as glycosides) have a crucial significance in providing ~20% protection against snake venom. Jj

Antioxidant activity

Studies on antioxidants are crucial, particularly in the food industry and in therapeutic research. The reactive oxygen species (ROS) and free radicals are byproducts of biological metabolism, which is responsible for cell membrane breakdown, membrane protein damage, and DNA mutation. These can further initiate the development of many diseases such as cancer, liver injury, cardiovascular diseases, cellular damage, and the aging process. [22],[23],[24],[25],[26],[27] The indigenous enzymatic systems (superoxide dismutase, glutathione peroxidase, catalase), chemical scavengers and dietary antioxidants (α-tocopherol, β-carotene, ascorbic acid, glutathione, uric acid), and hormones (estrogen, angiotensin) are able to remove free radicals formed in cells and thus protect against oxidative damage. [22],[23] Further, antioxidant phytochemicals found in several medicinal plants, fruits, and vegetables also protect the human body from disease by scavenging ROS and free radicals. [24],[25],[26],[27],[28] TheCadamba is a medicinal plant known to have antioxidant properties that are found particularly in its leaves. [29]Antioxidant properties in the ethanolic extract of the Cadambaleaves were assayed by estimating liver and kidney tissue enzymes using the 2'- diphenyl-1-picrylhydazyl (DPPH) assay, the superoxide anion radical scavenging assay, and DNA damage. It was found that the Cadamba possesses potent antioxidant properties. Further, UPLC-ESI-QTOF/MS has also confirmed the presence of various bioactive compounds from the Cadamba leaves having antioxidant properties. 

Biological significance

• Antihelminthic activity

Recently, the antihelminthic activity of the Cadamba has been elucidated. It was examined on adult Indian earthworms,Pheritima posthuma, due to its anatomical and physiological resemblances with the intestinal roundworm parasites of the human beings. Each group was treated with aqueous and ethanolic extracts of the mature bark of the Cadamba with varied concentrations ranging from 10 mg/ml to 25 mg/ml along with vehicle (piperazine citrate, 15 mg/ml, prepared in 1% tween-80). [32],[33] It was observed that paralysis and subsequently death of an individual worm have taken almost 4 h. Here paralysis was said to occur when the normal worm did not revive in saline, while death was concluded to have occurred when the worms lost their motility followed by the fading of their body color.

• Antifungal activity

Patel et al. [] have demonstrated the antifungal property of the Cadamba. They have reported that the extract of the bark and leaf of the Cadamba showed antifungal activity againstAspergillus fumigatus and Candida albicans. They have also found that the Cadamba leaf extract shows higher antifungal activity than the bark extract.

• Antifilarial and antimalarial activities

Mosquito-borne diseases like malaria, dengue, chikungunya, filariasis, and Japanese encephalitis cause thousands of deaths per year in India as well as in other developing countries. Therefore, mosquito control is a serious concern and necessary to enhance the health and quality of life of the country's residents and visitors. The management of vector-borne diseases has failed due to their increased resistance and revitalization against synthetic chemicals. There is a number of reports on the use of plant extracts for killing mosquito larvae. Recently, it was reported that Cadamba leaf extract has excellent larvicidal and pupicidal activities against the filarial vector, Culex quinquefasciatus, even at low concentrations. It was found that the methanolic extract ofCaamba leaves was most effective against stage I, i.e. the larval stage, where 46% mortality was observed at 5 ppm and increased to 100% at 80 ppm. The observed LC 50 and LC 90values were 12.15 ppm and 56.62 ppm, 15.15 ppm and 64.72 ppm, 21.82 ppm and 79.52 ppm, and 31.29 ppm and 102.13 ppm against stages I, II, III, and IV of larval pupae, respectively. Moreover, the addition of gold nanoparticles to the extract has proved to be more lethal, leading to 100% mortality at the larval stage at a very low concentration with LC 50 at 0.61 ppm. There is another study, which found that the dimethyl sulfoxide extract of the Cadamba shows antimalarial activity with LC 50 of 3.7 μg/ml against Plasmodium falciparum, K1 strain. [

• Antibacterial activity

The alcoholic and aqueous extracts of Cadamba fruits have shown significantly higher antibacterial activity against microorganisms (Staphylococcus aureus,  Escherichia More Details coli, Pseudomonas aeruginosa, Micrococcus luteus, Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa,  Salmonella More Details typhi, Klebsiella pneumonia, Proteus mirabilis, Candida albicans, Trichophytonrubrum, Asperagillus niger, Asperagillus flavus, and Asperagillus nidulans). An experiment demonstrated by Mishra et al. concluded that the antibacterial properties ofCadamba have zones of inhibition as 22.0 cm and 24.0 cm against E. coli and P. aeruginosa, respectively, at minimum inhibitory concentration (MIC) of 1.00 mg/ml. The extract ofCadamba was also effective against the foot and mouth disease of animals.  Further, the aqueous extract ofCadamba was effective against Rathyibacter tritici, a causal organism of tundu disease of wheat. 

Pharmacological significance of phytochemicals of Cadamba

• Antidiabetic activity

Diabetes mellitus is a metabolic disorder characterized by hyperglycemia and alterations in carbohydrate, fat, and protein metabo  Different types of oral hypoglycemic agents are available in the market for the treatment of diabetes mellitus. There is a growing interest in herbal remedies due to the various side effects associated with these therapeutic agents. Herbal drugs have higher efficacy, minimal side effects, and have a relatively low cost. Bussa et al. demonstrated an experiment to determine the antidiabetic study of Cadamba in which they have used the Cadamba stem bark which contains flavonoids (7.83 mg) and phenolic acids (12.26 mg) per 100 g of dry weight of the stem bark powder. The effect of the different doses of ethanolic extract ofCadamba stem bark on the fasting blood glucose levels of both normal and diabetic mice was studied. It was found that the fasting blood glucose levels of diabetic untreated mice were significantly higher than those of normal untreated rats. The ethanolic extracts of Cadamba bark powder extract at a dosage of 0.5 g/kg produced a fall of 23.8% in the blood glucose levels of diabetic rats after 5 h of day.



• Antitumor activity

Cancer is a term used for a disease in which abnormal cells tend to proliferate in an uncontrolled way and in some cases metastasize. Extensive research has been done to find therapeutic treatments for cancer. Plant-based products have been frequently examined as potential anticancer agents. The screening of various medicinal plants has found several bioactive compounds which are effective chemopreventive as well as chemotherapeutic agents. The phytochemical screening of Cadamba has revealed the presence of lupeol and betulinic acid-type triterpene which have antineoplastic activity.  Antitumor activity of defatted methanol extract ofCadamba (MEC) on Ehrlich ascites carcinoma (EAC) has been evaluated. [44] There was extensive in vitro cytotoxicity as found by trypan blue and in vivo antitumor activity was evaluated by inoculating groups of mice with EAC. The antitumor potential of MEC was assessed by evaluating tumor volume, viable and nonviable tumor cell count, tumor weight, hematological parameters, and biochemical estimations. Finally, MEC exhibited significant decrease in the above mentioned parameters in EAC tumor-bearing mice. Further, the hematological profile, biochemical estimations, and tissue antioxidant assay were reverted to normal level in MEC treated mice.

• Analgesic and Anti-inflammatory activities

Flavonoids in Cadamba like quercetin, silymarin apigenin, daidzein, and genistein are known to have analgesic and anti-inflammatory activities. [45],[46] Research is being done to identify more and more active constituents in Cadamba having anti-inflammatory activity. Anti-inflammatory activities ofCadamba are studied using active enzyme expressions of cyclooxygenase and lipoxygenase. Further, intact lysosomal membrane is important as the release of lysosomal constituent of activated neutrophil such as bacterial enzymes and proteases occurs during tissue inflammation. It has been reported that ethanolic extract of Cadamba leaves exhibited significant membrane stability as found from heat induced hemolytic effect on erythrocyte membrane .

• Antidiarrheal activity

The dry hydroethanolic extract of the flowering tops of theCadamba has exhibited a dose-dependent decrease in the frequency of fecal droppings in castor oil-induced diarrhea in mice. The extract also produced a dose-dependent reduction in intestinal fluid accumulation.

• Hypolipidemic activity

It has been found from experimental studies that alloxan has the capacity of reducing lipid levels by 30% as observed in diabetic mice. In comparison to this drug, the oral administration of root extract of the Cadamba for 30 days in dyslipidemic animals resulted in a significant decrease by 80% in total cholesterol, phospholipids, triglycerides, and lipid peroxides, with a reduction in lipid levels in diabetic 

• Antihepatotoxic effects

The Cadamba has been reported to be used for its hepatoprotective activity. The hepatoprotective activity is due to the presence of chlorogenic acid (CGA) isolated from theCadamba plant. It was also found that the intraperitoneal administration of CGA to mice at a dose of 100 mg/kg for 8 days exhibited better liver protective action than silymarin (SM) in CCl 4 . The study concluded that, surprisingly, the antioxidative activity of CGA prepared in CCl 4 is responsible for its hepatoprotective nature in mice model with liver injury.

•Diuretic and laxative activitiesf

Mondal et al. [51] have studied the extracts of bark of theCadamba in various concentrations in different solvents and demonstrated its diuretic and laxative activities. They have reported that the methanolic extract of Cadamba bark showed significant increase in urinary output as compared to aqueous, chloroform, and petroleum ether extracts. Moreover, there was higher laxative activity in case of the chloroform extract than with respect to the methanol, petroleum, and aqueous extracts.


    Conclusion  


The Cadamba is an important plant having tremendous medicinal properties. This review has showcased various biological and pharmacological activities of the Cadamba. Particularly, the leaves and bark have great significance. Most surprisingly, despite the Cadamba being a miraculous plant, very few studies have been done. There are very few derived products from the Cadamba known so far that have been commercialized or been recommended in daily life for people. There is an urgent requirement for intensive studies on this plant to exploit it for the treatment of various incurable diseases prevalent across the world.


   

  

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