Download Ready made project PPT Bioactivity guided isolation of Acyl CoA: Monoglyceride acyl transferase (MGAT) inhibitor from the stem bark of Anthocephalus indicus

Download project ppt on Bioactivity guided isolation of Acyl CoA: Monoglyceride acyl transferase (MGAT) inhibitor from the stem bark of Anthocephalus indicus

Conclusion:

From our data we can conclude that methanolic extract and its chloroform fraction of Anthocephalus indicus possess MGAT inhibitory activity. Further bioactivity guided fractionation of the chloroform fraction is needed to isolate the compounds responsible for MGAT inhibition.

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Donwload Design, Synthesis and Docking study of N-substituted 2,4- Thiazolidinedione as Cytotoxic Agents

SUMMARY

Download Design, Synthesis and Docking study of N-substituted 2,4- Thiazolidinedione as Cytotoxic Agents

·         Introduction about anticancer agents have been studied.

·         Chemistry and biological importance of 2,4-thiazolidinedione have also been studied.

·         Various literatures regarding N-substituted 2,4-thiazolidinedione with biological activity have been reviewed.

·         Docking study on the ERK2 receptor has been done by AUTODOCK 4.2 software. And 132 compounds were predicted.

·         Different 8 good docking scoring  N-substituted 5-arylidine 2,4-thiazolidinedione derivatives have been synthesized.

·         All the synthesized compounds were characterized by IR, Mass and 1H NMR spectroscopy.

·         MTT solution (5 mg/ml in phosphate buffered saline (PBS) pH 7.5), HCl, Propan-2-ol  96-well micro titer plate, ELISA reader.

·         The in vitro cytotoxic activity were performed against human carcinoma cell lines: NCI-H292 (obtained from muco epidermoid carcinoma of lung), HEp-2 (obtained from epidermoid carcinoma of the larynx), MDA MB-231(brest cancer cell line), A375( human melanoma cell line).

·         Normal cell line : HEK 293P

·         X 104  Cell were grown in micro titer plates in a final volume of 100 µl culture medium per well. Cells were incubated for 24 hr at 37˚C & 5% CO2.

·         Various amounts of compound were added (final concentration e.g. 100µM - 0.005µM) into micro plates (96 wells, flat bottom).

·         After incubation period, 10 µL of the MTT labeling mixture were added.

·         Plate was allowed for incubation 4 hr at 37˚C under CO2 incubator.

·         Then 100 µl solubilization solution were added.

·         Absorbance were measured with use Microplate reader at 590 nm (reference wavelength of 650 nm).

·         Thesis is under process by Dhaval Shah.

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Job Vacancies in MNC Pharma

* . Jobs in Emcure Pharmaceuticals ,

In analysis and Validation of finished product, Gandhinagar, Gujarat

Requirements are .
A) 5 candidates required urgently for Finished Product Routine Analysis & Validation.
Education: MPharm / MSc (if experienced) Experience: 4-6 yrs.
Location: Emcure Pharmaceuticals Limited, Adalaj, Gandhinagar.

mail: joseph.ambrose@emcure.co.in



.*  Officer/Executive QA Location- Jhagadia(Near Bharuch) GUJARAT

Position- Officer/Executive QA

Location- Jhagadia(Near Bharuch)

CTC- Best in the industry

Job Profile:

1. Sampling & Composite Sample Preparation

2. Physical Analysis of Powder (pH, BD, Viscosity on Brookfield, Colour on Hunter Colour Lab, Water Activity, Dispensability) etc.

3. Chemical Analysis of In Process & Finishes Goods (Protein by Keltic, Fat by Mojonnier, Moisture on halogen, Chloride & Iodide on ISE etc.)

4. Water Analysis (TDS & Chlorine)

5. Oil Analysis (FFA, PV, Moisture, Rancimat, p- anisidine etc.)

6. Calibration & Routine Maintenance of Instruments

Pease do revert with the following information to enable further
discussions/process in case you are interested
1. Your updated CV
2. Current Role:-
5. Current & Expected CTC
6. Your consent to process your candidature for the said assignment
7. Whether you would be willing to relocate to -

Strategically...
Radhika
Task Staffing Solutions Pvt. Ltd.
radhika@taskstaffing.com
079-40205035

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Urgent Pharma Jobs

Walk-In interview for QC &QC Micro parenteral at Amneal pharma.


Job Location : Ahmedabad
Date : 17 january 2016 (Sunday)
Timings: 9:30 am to 1:30 pm

Walk-In-Interview Venue   :
Amneal Pharmaceuticals Pvt Ltd, 5th floor, 508-514, Venus Atlantis Corporate park, Prahladnagar Road,
Ahmedabad-380051
Contact        :
We Amneal Pharmaceuticals pvt Ltd represent a new generation of generics. Amneal pharmaceuticals L.L.C has grown from a small OTC Contract manufacturer to high-quality producer of both solid, Liquid & Injectable generic prescription pharmaceutical products.
Our company started in Paterson, New Jersey and remains headquartered there today with new facilities sprouting up all the globe. We now operate in Glasgow,Kentucky, Branchburg and Fairfield, New jersey, Ahmedabad, Dahej, Gujarat,  Hydrabad, Vishakhapatnam and long island, New york. Amneal continues to manufacture all of our own product's in the united states under the strictest of guidelines


If you have the talent and the zeal here’s an opportunity for you to join our Injectable manufacturing plant at Ahmedabad as:

(1) Officer/Sr.officer/Executive/Sr.Executive - Quality Control - (50 Vacancies)

(2) Officer/Sr.Officer/Sr. Executive/Executive
-- QC Micro (10 Vacancies)
For above position following education  required  like
B.Sc. / B.Pharm / M.Sc/M.pharm with 1 to 8 years of experience

Candidates must have exposure to regulatory requirements of documentation and cGMP/GLP .

Interested candidates may “Walk-in” for an interview along-with their updated CVs and relevant documents.

Those who are unable to attend walk in interview they can also share there CV on chandanid@amnealindia.com
(Fresher can only share there CV on above mail I'd only)
Regards,
Team HR.Walk-In interview for QC &QC Micro parenteral at Amneal pharma.

Job Location : Ahmedabad
Date : 17 january 2016 (Sunday)
Timings: 9:30 am to 1:30 pm

Walk-In-Interview Venue   :
Amneal Pharmaceuticals Pvt Ltd, 5th floor, 508-514, Venus Atlantis Corporate park, Prahladnagar Road,
Ahmedabad-380051
Contact              :
We Amneal Pharmaceuticals private  Ltd represent a new generation of generics. Amneal pharmaceuticals L.L.C has grown from a small OTC Contract manufacturer to high-quality producer of both solid, Liquid & Injectable generic prescription pharmaceutical products.
Our company started in Paterson, New Jersey and remains headquartered there today with new facilities sprouting up all the globe. We now operate in Glasgow,Kentucky, Branchburg and Fairfield, New jersey, Ahmedabad, Dahej, Gujarat,  Hydrabad, Vishakhapatnam and long island, New york. Amneal continues to manufacture all of our own product's in the united states under the strictest of guidelines


If you have the talent and the zeal here’s an opportunity for you to join our Injectable manufacturing plant at Ahmedabad as:

(1) Officer/Sr.officer/Executive/Sr.Executive - Quality Control - (50 Vacancies)

(2) Officer/Sr.Officer/Sr. Executive/Executive
-- QC Micro (10 Vacancies)
For above position following education  required  like
B.Sc. / B.Pharm / M.Sc/M.pharm with 1 to 8 years of experience

Candidates must have exposure to regulatory requirements of documentation and cGMP/GLP .

Interested candidates may “Walk-in” for an interview along-with their updated CVs and relevant documents.

Those who are unable to attend walkin interview they can also share there CV on chandanid@amnealindia.com
(Fresher can only share there CV on above mail I'd only)
Regards,
Team HR.

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Jobs In MNC pharmaceutical company

Here I have given jobs detail.

There is urgent requirement of QA person.

Walk in Interview For Injectable SEZ
                      For
QA as IPQA Validation  and QMS ,QCC ,QCC
In Micro Department
Date . 3rd January, 2016., Sunday.
Timing. 10 am to 2 pm
Venue . 508-514, 5th Floor Venus Atlantic
              Corporate park,Prahladnagar,
              Ahmed a bad.
Job Location.  Ahmedabad matoa

Jobs Criteria.

• Minimum experience required is 1year.
• Please attend interview with updateD resume, salary slip,ctc,& photograph.
• USFDA, MHRA knowledge will be added an advantage. 

Note . Those who are unable to attend interview  they can share their CV on manoj@amealindia.com, chandanid@amnealindia.com and B.pharmaceutical. , M.pharmaceutical, fresher b.sc. and m.sc. can also drop their CV.

Please  attend  interview 

And best of luck for tomorrow.
And please share this postwith your friends. 

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